Manchester United travel to Bristol City to begin the defense of their English Football League Cup now renamed the Carabao Cup.
United, who defeated Swansea City 2-0 in the fourth round, will head to Ashton Gate to take on the Championship side, who dumped Crystal Palace after securing a 4-1 in the previous round.
Chelsea were drawn against Bournemouth while Arsenal have a London derby with West Ham who came from two goals down to secure a 3 - 2 win at Wembley.
Five-time winners Chelsea defeated Everton 2 - 1 in the fourth round while Bournemouth got the better of Middlesbrough in a 3-1 victory.
Arsenal fought back from a goal down to beat Norwich City 2-1 thanks to a double from youngster Eddie Nketiah last time out.
Leicester City who saw off Leeds United 3 - 1 in the fourth round face Manchester City who needed penalties to dump Wolves.